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By: Adapted from eGuidelines+ by Rachelle Williams MSN, RN, CNOR
Published: 9/11/2023
Before the patient enters the OR, confirm what prepping agent will be used; this will allow you to verify with the patient any allergies and assess for any open areas near the incision site, which may contraindicate an agent’s use. Different resources may be used confirm the antiseptic agent to be used, such as the surgical preference card or preoperative huddle led by the surgeon. The manufacturer's instructions for use (IFU) for the antiseptic agent provides information that may affect application, including sites on which and patients in whom it should not be used or be used with caution.
The skin prep occurs before the surgical incision, but after the patient has been positioned. For abdominal procedures, the patient is positioned in supine or a modification of supine. Regardless of what antiseptic agent you will be using, prepare the supplies ahead of time and follow these steps:
It is recommended that a nonscrubbed team member apply the antiseptic using aseptic technique;1,2 if you are not performing the prep, it is your responsibility as the patient advocate to ensure that the prep is being applied according to the manufacturer’s IFU using aseptic technique.
Alcohol-based antiseptics are considered superior in terms of clinical and antimicrobial effectiveness than other no-alcohol antiseptics.3 If an alcohol-based prep is used, it is imperative that you include it in your fire risk assessment calculation and follow the IFU for the dry time (eg, three minutes on hairless skin and up to one hour for hair).
There are two types of alcohol-based antiseptics: 2% chlorhexidine gluconate (CHG) with alcohol and iodine povacrylex with alcohol. The prefilled sterile applicators come in different sizes that contain a glass ampule of the prep solution. It is important that you choose the correct size according to the IFU for the surgical site area you are prepping (Table 1).4,5 Before starting the prep, you will need to activate the applicator. It is recommended that you let the solution flow freely (no shaking) to the applicator sponge. If you are using an applicator that is long enough to avoid contact with the gloved hand, antiseptic, and patient’s skin, you can don nonsterile gloves. If there is a potential risk for contamination, you should don sterile gloves.1,2
Table 1. Applicator sizes and prep areas for 2% CHG with alcohol and iodine povacrylex with alcohol
Solution | Applicator size | Prep area |
2% CHG with alcohol | 26 mL | 13.3 in x 13.2 in |
10.5 mL | 8.4 in x 8.4 in | |
3 mL | 4 in x 5in | |
1 mL | 2.5 in x 2.5 in | |
Iodine povacrylex with alcohol | 26 mL | 15 in x 30 in |
After the procedure, the prep should remain on the patient to provide continued antimicrobial activity. This should be discussed with the patient and their family preoperatively, so they are not surprised when they see the prep on the patient’s skin.
The CHG prep comes in two different tints: orange and teal. The orange tint is more visible on fair skin tones whereas the teal tint is more visible on medium to dark skin pigmentation.6 To prep with 2% CHG with alcohol:
When prepping with iodine povacrylex with alcohol, perform the steps listed for 2% CHG with alcohol, but do not use a back-and-forth motion. Instead, paint the prep on, which means that you move from clean to dirty without going over an already prepped area.7
Alternatives to alcohol-based antiseptics, if not contraindicated, include 4% CHG, povidone-iodine scrub and paint, and chloroxylenol 3% (PCMX).8 These agents do not come in a prefilled applicator. They require a sterile set-up opened on a prep stand. The contents opened could include a small basin(s), sponge sticks, and 4 x 4 gauze (some sites will only use 4 x 4 sterile radiopaque sponges or a premade kit with foam sponges).
After performing hand hygiene:
It should be noted that these agents will get wiped off the patient after the procedure.
When prepping with 4% CHG,
When prepping with povidone-iodine scrub and paint,
This antiseptic can be applied the same as 4% CHG; however, it could be left to dry or blotted with a sterile towel.
If a patient has a stoma near the incision site, prep the area with the lower bacterial count first and then the site with the higher count.
Editor's note: This content is adapted from AORN eGuidelines+. If your facility subscribes to eGuidelines+, you can access the full content. This article is intended to serve as a guide to prepping and may not represent every available antiseptic solution. Always prep in accordance with the manufacturer’s instructions for use for the antiseptic solution being used. AORN does not endorse any commercial company’s products or services, including particular skin preparation products. Inclusion of a solution in this article does not constitute an endorsement by AORN of the quality or value of such solution or process, or of the claims made by its manufacturer.
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